Description

Pyridine, 3-Chloro-5-Ethynyl is a halogenated and alkynyl-substituted pyridine derivative, serving as a versatile and high-value synthetic building block. Its unique molecular architecture, featuring both a chloro and an ethynyl group on the pyridine ring, makes it a critical intermediate for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and advanced materials chemists for applications in medicinal chemistry, ligand synthesis, and polymer science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other targeted therapy research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Ligand & Catalyst Development: The ethynyl group enables its use in click chemistry and as a precursor for sophisticated ligands in homogeneous catalysis.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers, conductive materials, and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in organic synthesis and methodology development.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex dyes, pigments, and other high-value fine chemicals.

Basic Information

Product Name	Pyridine, 3-Chloro-5-Ethynyl
CAS No.	329202-22-4
Molecular Formula	C7H4ClN
Molecular Weight	137.57 g/mol
Synonyms	3-Chloro-5-ethynylpyridine; 5-Ethynyl-3-chloropyridine; 3-Chloro-5-ethynyl-pyridine; 3-Chloro-5-pyridylacetylene; 3-Chloro-5-(ethynyl)pyridine
EINECS	Contact for details

Quality Control

Our Pyridine, 3-Chloro-5-Ethynyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.