Description

tert-Butyl 3-(4-Bromophenyl)Pyrrolidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its pyrrolidine core and bromophenyl substituent. This compound is a critical building block in modern organic synthesis, enabling the construction of complex molecules with high precision and yield. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated aromatic structure.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic materials.
• Academic & R&D: Employed in university and industrial laboratories for methodological studies in cross-coupling reactions and heterocyclic chemistry.
• Ligand & Catalyst Development: Acts as a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	tert-Butyl 3-(4-Bromophenyl)Pyrrolidine-1-Carboxylate
CAS No.	328546-99-2
Molecular Formula	C15H20BrNO2
Molecular Weight	326.23 g/mol
Synonyms	1-Boc-3-(4-bromophenyl)pyrrolidine; tert-Butyl 3-(p-bromophenyl)pyrrolidine-1-carboxylate; 3-(4-Bromophenyl)-1-(tert-butoxycarbonyl)pyrrolidine; 1-(tert-Butoxycarbonyl)-3-(4-bromophenyl)pyrrolidine; 3-(4-Bromophenyl)pyrrolidine-1-carboxylic acid tert-butyl ester; Boc-3-(4-Bromophenyl)pyrrolidine; 328546-99-2; 3-(4-Bromophenyl)-N-Boc-pyrrolidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(4-Bromophenyl)Pyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.