Description

(4-Amino-2-Methyl-Phenyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected aniline derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals, where its protected amino group offers precise control over reaction pathways. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex multi-step syntheses.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific aniline-based architectures.
• Fine Chemical Production: Serves as a versatile building block for creating complex dyes, pigments, and photographic chemicals.
• Peptide & Polymer Chemistry: Utilized in the preparation of specialty monomers and protected amino acid analogs for advanced material science.
• Research & Development: An essential reagent in academic and industrial R&D labs for method development and exploring new synthetic routes.
• Custom Synthesis: The starting point for contract manufacturing organizations (CMOs) producing bespoke compounds for client-specific projects.

Basic Information

Product Name	(4-Amino-2-Methyl-Phenyl)-Carbamic Acid tert-Butyl Ester
CAS No.	325953-40-0
Molecular Formula	C12H18N2O2
Molecular Weight	222.28 g/mol
Synonyms	tert-Butyl (4-amino-2-methylphenyl)carbamate; N-Boc-4-amino-2-methylaniline; N-(tert-Butoxycarbonyl)-4-amino-o-toluidine; 2-Methyl-4-[(tert-butoxycarbonyl)amino]aniline; Boc-4-Amino-2-methylaniline; 4-Amino-2-methylphenylcarbamic acid 1,1-dimethylethyl ester; 4-Amino-2-methylaniline N-Boc protected; N-Boc-2-methyl-p-phenylenediamine
EINECS	Contact for details

Quality Control

Our (4-Amino-2-Methyl-Phenyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.