Description

1-(4-Fluorophenyl)Sulfonyl-2-Methyl-5-Nitroimidazole is a high-purity, advanced pharmaceutical intermediate characterized by its specific sulfonyl and nitroimidazole functional groups. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutic agents. It is primarily utilized by research institutions and manufacturers in the global pharmaceutical and agrochemical industries for drug discovery and process chemistry applications.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new nitroimidazole-based drug candidates with potential antimicrobial or antiparasitic activity.
• Agrochemical Research: Used in the development of novel fungicides or herbicides, leveraging its bioactive imidazole core.
• Chemical Synthesis: Serves as a versatile precursor for further chemical modifications, including sulfonamide coupling reactions, in medicinal chemistry.
• Academic & R&D: Employed in university and corporate research laboratories for studying structure-activity relationships (SAR) and developing new chemical entities.
• Process Development: Used by API manufacturers for scaling up synthetic routes and optimizing production processes for clinical trial materials.

Basic Information

Product Name	1-(4-Fluorophenyl)Sulfonyl-2-Methyl-5-Nitroimidazole
CAS No.	325813-19-2
Molecular Formula	C10H8FN3O4S
Molecular Weight	285.25 g/mol
Synonyms	1-[(4-Fluorophenyl)sulfonyl]-2-methyl-5-nitro-1H-imidazole; 2-Methyl-1-(4-fluorophenylsulfonyl)-5-nitroimidazole; 1-(p-Fluorophenylsulfonyl)-2-methyl-5-nitroimidazole; 5-Nitro-2-methyl-1-(4-fluorophenylsulfonyl)imidazole; 1H-Imidazole, 1-[(4-fluorophenyl)sulfonyl]-2-methyl-5-nitro-; CAS 325813-19-2
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)Sulfonyl-2-Methyl-5-Nitroimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants and maintaining an inert atmosphere to minimize oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.