Description

Methanesulfonamide, n-Cyano-1,1,1-Trifluoro- is a specialized organofluorine building block characterized by its unique combination of a cyano group and a trifluoromethylsulfonamide moiety. This compound matters for its role as a key intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where its structure imparts desirable biological activity and metabolic stability. It is primarily needed by research and development chemists and process scale-up teams in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients.

Application

• Agrochemical Intermediate: A critical synthon for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profile.
• Pharmaceutical Building Block: Used in the research and synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) and metabolic diseases.
• Material Science Research: Serves as a precursor for functional materials, including liquid crystals and polymers with specific electronic or surface properties.
• Fluorination Chemistry: Employed in medicinal chemistry to introduce the trifluoromethylsulfonamide (TFMS) group, a bioisostere known to improve pharmacokinetic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule development and scale-up projects.

Basic Information

Product Name	Methanesulfonamide, n-Cyano-1,1,1-Trifluoro-
CAS No.	325801-49-8
Molecular Formula	C3H2F3N2O2S
Molecular Weight	187.12 g/mol
Synonyms	2,2,2-Trifluoro-N-cyanomethanesulfonamide; N-Cyano-1,1,1-trifluoromethanesulfonamide; Trifluoromethanesulfonamide, N-cyano-; 1,1,1-Trifluoro-N-cyanomethanesulfonamide; TFMS-CN; N-Cyano trifluoromethanesulfonamide; α-Cyano-α,α,α-trifluoromethanesulfonamide; (Cyanoamino)sulfonyl-1,1,1-trifluoromethane
EINECS	Contact for details

Quality Control

Our Methanesulfonamide, n-Cyano-1,1,1-Trifluoro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.