Description

4-Chloro-2-Fluoro-5-Methoxycarbonylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, especially those containing biaryl motifs, via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific halogenated aromatic frameworks.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis or as a scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target identification.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-Methoxycarbonylphenylboronic Acid
CAS No.	325786-24-1
Molecular Formula	C8H7BClFO4
Molecular Weight	231.40 g/mol
Synonyms	(4-Chloro-2-fluoro-5-(methoxycarbonyl)phenyl)boronic acid; 5-Borono-2-chloro-4-fluorobenzoic acid methyl ester; Methyl 5-borono-2-chloro-4-fluorobenzoate; 2-Chloro-4-fluoro-5-methoxycarbonylphenylboronic acid; 4-Chloro-2-fluoro-5-(methoxycarbonyl)benzeneboronic acid; CAS 325786-24-1
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-5-Methoxycarbonylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.