Description

5-Carboxy-4-Chloro-2-Fluorophenylboronic Acid is a high-purity, multi-functional boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in its unique molecular structure, which combines a boronic acid group with halogen and carboxylic acid functionalities, enabling precise cross-coupling reactions and further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its halogenated aromatic structure for bioactivity.
• Material Science Research: Employed in the creation of organic electronic materials and metal-organic frameworks (MOFs) due to its ability to form stable boron-containing complexes.
• Chemical Biology Probes: Serves as a versatile handle for bioconjugation and the development of sensors or diagnostic tools.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, complex boronic acid derivatives.

Basic Information

Product Name	5-Carboxy-4-Chloro-2-Fluorophenylboronic Acid
CAS No.	325786-23-0
Molecular Formula	C7H5BClFO4
Molecular Weight	217.38 g/mol
Synonyms	(5-Carboxy-4-chloro-2-fluorophenyl)boronic acid; 4-Chloro-2-fluoro-5-carboxyphenylboronic acid; 2-Fluoro-4-chloro-5-boronobenzoic acid; Boronic acid, B-(5-carboxy-4-chloro-2-fluorophenyl)-; 325786-23-0; 5-Carboxy-4-chloro-2-fluorobenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Carboxy-4-Chloro-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and elemental analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.