Description

2,4-Difluoro-5-Nitrophenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both electron-withdrawing nitro and fluorine substituents, makes it an indispensable reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the bioactivity of the difluoro-nitrophenyl motif.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its structure aids in tuning electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized boronic ester ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the synthesis of activity-based probes and sensors for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses serving the global fine chemical market.

Basic Information

Product Name	2,4-Difluoro-5-Nitrophenylboronic Acid
CAS No.	325786-11-6
Molecular Formula	C6H4BF2NO4
Molecular Weight	202.91 g/mol
Synonyms	(2,4-Difluoro-5-nitrophenyl)boronic acid; 2,4-Difluoro-5-nitrobenzeneboronic acid; 5-Nitro-2,4-difluorophenylboronic acid; B-(2,4-Difluoro-5-nitrophenyl)boronic acid; 325786-11-6; 2,4-Difluoro-5-nitrophenyl-B(OH)2; Boronic acid, B-(2,4-difluoro-5-nitrophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-5-Nitrophenylboronic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.