Description

3-Trifluoromethylphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in its enhanced stability and handling properties compared to the free boronic acid, making it indispensable for complex multi-step syntheses. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key synthon for constructing biaryl and heterobiaryl scaffolds prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides containing trifluoromethylphenyl motifs.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as OLEDs and semiconductors, via cross-coupling polymerization.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and target engagement.
• Scale-up Process Chemistry: Its pinacol ester form offers superior stability for reliable use in kilo-lab and pilot plant manufacturing.

Basic Information

Product Name	3-Trifluoromethylphenylboronic Acid, Pinacol Ester
CAS No.	325142-82-3
Molecular Formula	C₁₃H₁₆BF₃O₂
Molecular Weight	272.07 g/mol
Synonyms	3-(Trifluoromethyl)benzeneboronic Acid Pinacol Ester; (3-(Trifluoromethyl)phenyl)boronic Acid Pinacol Ester; 3-Trifluoromethylphenylboronic Acid Pinanediol Ester; 3-CF3-Phenyl-Bpin; 3-Trifluoromethylphenyl-Bpin; 1,3,2-Benzodioxaborole, 2-(3-(Trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-; B-(3-(Trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3-Trifluoromethylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.