Description

Bicyclo[2.2.1]Heptane-2-Acetonitrile, 2-Hydroxy-1,3,3-Trimethyl-, (1R,2R,4S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block featuring a rigid norbornane skeleton. This compound is valued for its ability to impart unique three-dimensional structure and stereochemical control in advanced synthetic pathways. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides with enhanced stereospecific activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and organocatalysts.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and stereochemistry.
• Flavor & Fragrance Chemistry: Potential use in synthesizing complex odorants and flavor molecules with specific stereoisomeric profiles.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Heptane-2-Acetonitrile, 2-Hydroxy-1,3,3-Trimethyl-, (1R,2R,4S)-Rel- (9Ci)
CAS No.	324538-17-2
Molecular Formula	C12H19NO
Molecular Weight	193.29 g/mol
Synonyms	(1R,2R,4S)-2-Hydroxy-1,3,3-trimethylbicyclo[2.2.1]heptane-2-acetonitrile; rel-(1R,2R,4S)-2-Hydroxy-1,3,3-trimethylbicyclo[2.2.1]heptane-2-acetonitrile; 2-Hydroxy-1,3,3-trimethylbicyclo[2.2.1]heptane-2-acetonitrile (rel-(1R,2R,4S)-form); Norbornane-based chiral acetonitrile; Hydroxynorbornane acetonitrile derivative
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-2-Acetonitrile, 2-Hydroxy-1,3,3-Trimethyl-, (1R,2R,4S)-Rel- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and stereochemical purity suitable for demanding R&D applications. A detailed Certificate of Analysis (COA) with full chromatographic data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.