Description

1-Stearoyl-2-Oleoyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) is a high-purity, synthetic phospholipid, specifically a sodium salt of phosphatidylglycerol (PG) with a defined fatty acid composition. This compound is critical for creating biomimetic membrane systems and serves as a key functional component in advanced drug delivery formulations, particularly liposomes. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and cosmetic industries who require precise lipid components for product development and quality control.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A critical excipient for constructing stable, anionic liposomal bilayers used in mRNA vaccines, cancer therapeutics, and other nanomedicines.
• Biomimetic Membrane Models: Used in biophysical research to create artificial cell membranes (e.g., vesicles, supported lipid bilayers) for studying protein-lipid interactions, membrane permeability, and fusion processes.
• Pulmonary Surfactant Research & Mimetics: Serves as a key component in studies and synthetic formulations aimed at mimicking natural lung surfactant for treating respiratory distress syndrome.
• Drug Delivery Enhancer: Improves the cellular uptake and bioavailability of encapsulated active pharmaceutical ingredients (APIs) due to its anionic charge and fusogenic properties.
• Cosmetic & Dermal Formulations: Incorporated into high-end skincare products as a biocompatible emulsifier and skin barrier repair agent.
• Diagnostic Reagent Component: Used in the development of diagnostic assays and kits that involve membrane-based detection systems.
• Cell Culture & Cryopreservation: Acts as a protective agent in specialized cell culture media and cryoprotectant solutions.

Basic Information

Item	Information
Product Name	1-Stearoyl-2-Oleoyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt)
CAS No.	322647-48-3
Molecular Formula	C44H84NaO10P
Molecular Weight	827.10 g/mol
Synonyms	SOPG (Sodium Salt); 1-Stearoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; PG(18:0/18:1) Sodium Salt; Phosphatidylglycerol (18:0/18:1) Sodium Salt; (2R)-2,3-Bis(octadec-9-enoyloxy)propyl (2,3-dihydroxypropyl) phosphate sodium salt; 1-Octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; POPG (variant naming); Synthetic Phosphatidylglycerol Sodium Salt
EINECS	Contact for details

Quality Control

Our 1-Stearoyl-2-Oleoyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and fatty acid composition, NMR for structural confirmation, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Our quality commitment supports applications in pharmaceutical development and critical research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). This product is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	Stearic Acid (C18:0): ~50%; Oleic Acid (C18:1): ~50%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.