Description

Ethyl 2,2-Difluoro-3-(4-Methoxyphenyl)Propanoate is a specialized fluorinated organic ester, serving as a critical building block in advanced chemical synthesis. Its value lies in the unique reactivity imparted by the difluoro and methoxyphenyl groups, enabling precise molecular construction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a difluoromethylenated backbone for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides where the fluorine atoms improve lipophilicity and biological activity.
• Liquid Crystal & OLED Material Research: Used in the development of fluorinated organic compounds for electronic display and lighting applications.
• Advanced Organic Synthesis: Versatile reagent for constructing complex molecules in medicinal chemistry and material science research programs.
• Custom Chemical Manufacturing: Serves as a starting material for contract research organizations (CROs) and CDMOs producing tailored compounds for client projects.

Basic Information

Product Name	Ethyl 2,2-Difluoro-3-(4-Methoxyphenyl)Propanoate
CAS No.	321856-71-7
Molecular Formula	C₁₂H₁₄F₂O₃
Molecular Weight	244.23 g/mol
Synonyms	Ethyl 2,2-Difluoro-3-(4-methoxyphenyl)propionate; 3-(4-Methoxyphenyl)-2,2-difluoropropanoic Acid Ethyl Ester; 2,2-Difluoro-3-(4-methoxyphenyl)propionic Acid Ethyl Ester; Ethyl 3-(4-Methoxyphenyl)-2,2-difluoropropanoate; Propanoic acid, 2,2-difluoro-3-(4-methoxyphenyl)-, ethyl ester; 321856-71-7; 4-Methoxyphenyl-difluoropropanoate ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2,2-Difluoro-3-(4-Methoxyphenyl)Propanoate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our products are suitable for demanding applications in regulated industries. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids, organic solvents, fluorides, and strong alkalis. The container must be kept tightly closed in a dry and inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.