Description

D-Phenylalanine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-β-Methyl-, (βs)- is a sophisticated, optically active amino acid derivative featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is critically important as a high-purity building block for solid-phase peptide synthesis (SPPS), enabling the precise construction of complex peptides with specific stereochemistry. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid precursor for the automated synthesis of therapeutic and research peptides.
• Pharmaceutical Intermediates: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Bioconjugation and Probe Development: Serves as a specialized component for creating labeled peptides, imaging agents, and diagnostic tools.
• Academic and Industrial Research: A valuable reagent for studying peptide structure-activity relationships (SAR) and developing peptide-based materials.
• Process Development: Employed in scaling up the production of peptide drugs under current Good Manufacturing Practice (cGMP) conditions.

Basic Information

Product Name	D-Phenylalanine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-β-Methyl-, (βs)-
CAS No.	321524-82-7
Molecular Formula	C26H23NO4
Molecular Weight	413.46 g/mol
Synonyms	Fmoc-β-Me-D-Phe-OH; (2S)-3-Phenyl-2-[(9H-fluoren-9-ylmethoxy)carbonylamino]propanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-phenyl-D-alanine; Fmoc-D-β-methylphenylalanine; Fmoc-D-3-phenylalanine; N-Fmoc-β-methyl-D-phenylalanine; BOC Sciences Brand Name: BBL-BB-0137
EINECS	Contact for details

Quality Control

Our D-Phenylalanine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-β-Methyl-, (βs)- is produced under stringent quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets the exacting standards required for peptide synthesis. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.