Description

2-Propenenitrile,3-(2S)-2-Pyrrolidinyl-,(2E)-(9Ci) is a high-purity, stereochemically defined chemical intermediate of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring a (2S)-pyrrolidinyl substituent and an (E)-configured acrylonitrile moiety, makes it a valuable building block for constructing complex, chiral molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets and other biologically active molecules.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic and Industrial Research: A valuable tool for methodological studies in organic chemistry, enabling exploration of new reaction pathways and stereochemical outcomes.

Basic Information

Product Name	2-Propenenitrile,3-(2S)-2-Pyrrolidinyl-,(2E)-(9Ci)
CAS No.	320776-35-0
Molecular Formula	C7H10N2
Molecular Weight	122.17 g/mol
Synonyms	(2E)-3-[(2S)-Pyrrolidin-2-yl]prop-2-enenitrile; (E)-3-((S)-Pyrrolidin-2-yl)acrylonitrile; (2E)-3-[(2S)-2-Pyrrolidinyl]-2-Propenenitrile; (E)-3-(L-Prolinol)acrylonitrile derivative; 320776-35-0; (E)-3-((S)-2-Pyrrolidinyl)acrylonitrile
EINECS	Contact for details

Quality Control

Our 2-Propenenitrile,3-(2S)-2-Pyrrolidinyl-,(2E)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure identity, strength, and composition. Certificates of Analysis (COA) detailing specific results for purity, enantiomeric excess, and related substances are provided with every shipment to guarantee reliable and consistent performance in your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.