Description

2-(4-Fluoroanilino)-1H-Isoindole-1,3(2H)-Dione is a specialized organic compound belonging to the isoindole-1,3-dione (phthalimide) class, distinguished by its 4-fluoroanilino substituent. This structural motif makes it a valuable high-purity intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, particularly in the development of kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting specific enzymes or receptors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the phthalimide core provides specific biological activity.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex heterocyclic compounds and functionalized molecules in organic chemistry.
• Material Science: Potential use in the research and development of specialty polymers, dyes, or photoactive materials.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe for studying biological pathways in academic and industrial research settings.

Basic Information

Product Name	2-(4-Fluoroanilino)-1H-Isoindole-1,3(2H)-Dione
CAS No.	320421-94-1
Molecular Formula	C14H9FN2O2
Molecular Weight	256.24 g/mol
Synonyms	N-(4-Fluorophenyl)phthalimide; 4-Fluoroanilinophthalimide; 1H-Isoindole-1,3(2H)-dione, 2-[(4-fluorophenyl)amino]-; 2-[(4-Fluorophenyl)amino]isoindoline-1,3-dione; 2-(4-Fluoroanilino)phthalimide; 2-Amino-N-(4-fluorophenyl)phthalimidine (incorrect but common search variant); 4-Fluoro-phenyl-phthalimide; FAP (abbreviation)
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoroanilino)-1H-Isoindole-1,3(2H)-Dione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and other critical parameters. Our quality systems are designed to support cGMP-compliant applications for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.