Description

2-Chloro-n-[3-Cyano-4-(Methylsulfanyl)Phenyl]-4,5-Difluorobenzenecarboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluorobenzene and cyano-substituted phenyl core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modulation. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its fluorinated aromatic system for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization via its reactive chloro, cyano, and methylsulfanyl groups.
• Material Science: Potential intermediate for creating specialized polymers or liquid crystals with unique electronic properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Item	Detail
Product Name	2-Chloro-n-[3-Cyano-4-(Methylsulfanyl)Phenyl]-4,5-Difluorobenzenecarboxamide
CAS No.	320421-42-9
Molecular Formula	C15H9ClF2N2OS
Molecular Weight	338.76 g/mol
Synonyms	2-Chloro-N-[3-cyano-4-(methylthio)phenyl]-4,5-difluorobenzamide; 4,5-Difluoro-2-chloro-N-[3-cyano-4-(methylsulfanyl)phenyl]benzamide; 320421-42-9; Benzamide, 2-chloro-N-[3-cyano-4-(methylthio)phenyl]-4,5-difluoro-; CAS 320421-42-9
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-n-[3-Cyano-4-(Methylsulfanyl)Phenyl]-4,5-Difluorobenzenecarboxamide adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity for critical R&D and scale-up processes. All materials are analyzed using advanced techniques including HPLC, GC, and NMR to verify identity and purity against established specifications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.