Description

5-(Bromomethyl)-2-Methoxybenzonitrile is a versatile brominated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and a methoxy-substituted benzonitrile core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Useful for creating tagged molecules and bioconjugates for studying biological pathways.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	5-(Bromomethyl)-2-Methoxybenzonitrile
CAS No.	320407-91-8
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	2-Methoxy-5-(bromomethyl)benzonitrile; 5-Bromomethyl-2-methoxybenzonitrile; 2-Methoxy-5-(bromomethyl)phenyl cyanide; Benzonitrile, 5-(bromomethyl)-2-methoxy-; (5-Bromomethyl-2-methoxyphenyl)cyanide; 320407-91-8; 5-Bromomethyl-o-anisonitrile
EINECS	Contact for details

Quality Control

Our 5-(Bromomethyl)-2-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.