Description

Pyrazolo[1,5-A]Pyridine-7-Carbonitrile, 2-Methyl- is a high-purity, nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and material science sectors for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or conductive polymers, due to its electron-deficient pyridine core.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for use in client-specific custom synthesis projects requiring specialized bicyclic frameworks.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyridine-7-Carbonitrile, 2-Methyl-
CAS No.	319432-37-6
Molecular Formula	C9H6N4
Molecular Weight	170.17 g/mol
Synonyms	2-Methylpyrazolo[1,5-a]pyridine-7-carbonitrile; 7-Cyano-2-methylpyrazolo[1,5-a]pyridine; 2-Methyl-7-cyanopyrazolo[1,5-a]pyridine; Pyrazolo[1,5-a]pyridine-7-carbonitrile, 2-methyl-; 319432-37-6; 2-Methylpyrazolo[1,5-a]pyridine-7-carbonitrile; 2-Methyl-7-pyrazolo[1,5-a]pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our Pyrazolo[1,5-A]Pyridine-7-Carbonitrile, 2-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.