Description

Benzene, 1-[(1E)-1,2-Difluoroethenyl]-4-Fluoro- (9Ci) is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its precise structure, featuring a difluoroethenyl substituent, makes it a valuable precursor for constructing complex molecules where the introduction of fluorine atoms is critical. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It enables the synthesis of novel active ingredients with potentially enhanced metabolic stability, bioavailability, and binding selectivity.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs into lead compounds.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where fluorination can improve efficacy and environmental profile.
• Material Science Research: Acts as a monomer or precursor for developing novel fluorinated polymers and liquid crystals with unique electronic or surface properties.
• Organic Electronics: Investigated for the synthesis of components used in OLEDs (Organic Light-Emitting Diodes) and semiconductor materials.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for studying biological mechanisms and diagnostics.
• Catalyst Ligand Development: Provides a framework for creating sophisticated ligand systems in transition metal catalysis.

Basic Information

Product Name	Benzene, 1-[(1E)-1,2-Difluoroethenyl]-4-Fluoro- (9Ci)
CAS No.	316173-80-5
Molecular Formula	C8H5F3
Molecular Weight	158.12 g/mol
Synonyms	4-Fluoro-1-[(1E)-1,2-difluoroethenyl]benzene; 1-[(1E)-1,2-Difluoroethenyl]-4-fluorobenzene; (E)-1-(1,2-Difluorovinyl)-4-fluorobenzene; 316173-80-5; 4-Fluorostyrene, 1,2-difluoro-; p-Fluoro-(E)-1,2-difluorovinylbenzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-[(1E)-1,2-Difluoroethenyl]-4-Fluoro- (9Ci) is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.