Description

Proline, 2-(2-Propenyl)- (9Ci) is a specialized proline derivative characterized by the presence of an allyl (2-propenyl) functional group. This structural modification makes it a valuable non-proteinogenic amino acid building block for advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and life science industries. The compound, with CAS number 315234-41-4, serves as a key chiral intermediate for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for peptidomimetics and enzyme inhibitors.
• Peptide Chemistry: Used as a modified amino acid residue in solid-phase and solution-phase peptide synthesis to introduce unique steric or functional properties into peptide chains.
• Agrochemical Research: Acts as a building block in the synthesis of advanced crop protection agents and herbicides that require specific chiral centers for optimal activity.
• Ligand Synthesis: Employed in the preparation of specialized ligands for asymmetric catalysis, facilitating the synthesis of enantiomerically pure compounds.
• Bioconjugation & Probe Development: Useful for creating chemical probes and bioconjugates due to the reactivity of the allyl group for further functionalization via click chemistry or cross-coupling reactions.
• Academic & Industrial R&D: A key material for methodological studies in organic synthesis and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	Proline, 2-(2-Propenyl)- (9Ci)
CAS No.	315234-41-4
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	2-Allylproline; (S)-2-Allylproline; L-2-Allylproline; 2-(Prop-2-en-1-yl)proline; 2-(2-Propen-1-yl)proline; 1-((S)-2-Allylpyrrolidine-1-carboxylic acid); 2-(Allyl)-L-proline; 2-(2-Propenyl)pyrrolidine-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our Proline, 2-(2-Propenyl)- (9Ci) is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing results for assay, chiral purity, and specific impurities. We support development and commercial projects with material that meets exacting R&D and cGMP standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). For long-term storage, consider holding the material under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.