Description

2-Fluoro-4-Nitrophenylacetic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic combination of a reactive carboxylic acid group, a nitro substituent, and a fluorine atom, enabling precise molecular modifications. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting specific enzymes or receptors where the fluorine atom enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the nitro and fluoro groups contribute to biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and liquid crystals, where its aromatic core and functional groups allow for fine-tuning of material properties.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or activity-based probes for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services for client-specific projects.

Basic Information

Product Name	2-Fluoro-4-Nitrophenylacetic Acid
CAS No.	315228-19-4
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	(2-Fluoro-4-nitrophenyl)acetic Acid; 2-(2-Fluoro-4-nitrophenyl)acetic Acid; 4-Nitro-2-fluorophenylacetic Acid; 2-Fluoro-4-nitrobenzeneacetic Acid; α-Carboxy-2-fluoro-4-nitro toluene; FNAA; 315228-19-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Nitrophenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.