Description

4-Boc-4-Ethylaminopiperidine is a high-purity, protected piperidine derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile nitrogen-containing scaffold with orthogonal protecting groups, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex active pharmaceutical ingredients (APIs) and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its piperidine core.
• Chemical Biology & Proteomics: Employed as a scaffold or linker for designing molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Peptidomimetics & Macrocycle Synthesis: Facilitates the creation of conformationally constrained peptide analogs and cyclic compounds for enhanced bioavailability and target selectivity.
• Material Science: Potential monomer or functionalization agent for specialty polymers and advanced materials with specific chemical functionalities.
• Academic & Contract Research: Serves as a valuable reagent for methodological development and exploratory synthesis in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	4-Boc-4-Ethylaminopiperidine
CAS No.	313977-45-6
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	1-Boc-4-(Ethylamino)piperidine; tert-Butyl 4-(ethylamino)piperidine-1-carboxylate; 4-(Ethylamino)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 4-Ethylamino-piperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-ethylaminopiperidine; 1-N-Boc-4-N-ethylpiperidine-1,4-diamine; 4-Ethylamino-1-N-Boc-piperidine
EINECS	Contact for details

Quality Control

Our 4-Boc-4-Ethylaminopiperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, for comprehensive identity confirmation and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, purity, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.