Description

(Cys39)-Tissue Factor (33-53) CAS NO 313642-01-2 is a synthetic peptide fragment corresponding to a specific region of human Tissue Factor, a key initiator of the blood coagulation cascade. This high-purity peptide is critical for advanced biochemical research and diagnostic development, particularly in the study of thrombosis, hemostasis, and related signaling pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and in vitro diagnostic (IVD) manufacturers requiring precise molecular tools for assay development and mechanistic studies.

Application

• Biochemical Research: Used as a specific antigen or binding partner in studies investigating the structure, function, and inhibition mechanisms of the Tissue Factor pathway.
• Diagnostic Assay Development: Serves as a critical component in the development and calibration of immunoassays (e.g., ELISA) for detecting Tissue Factor or related biomarkers.
• Antibody Production & Characterization: Employed for immunizing animals to generate specific antibodies or for screening hybridomas to identify monoclonal antibodies against Tissue Factor.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) platforms to identify and validate novel therapeutic compounds that modulate Tissue Factor activity.
• Quality Control Reference: Acts as a reference standard in the quality control of therapeutic biologics or diagnostic kits targeting the coagulation system.
• Cell Signaling Studies: Applied in cell-based assays to study the downstream effects of Tissue Factor signaling in vascular biology and oncology research.

Basic Information

Product Name	(Cys39)-Tissue Factor (33-53)
CAS No.	313642-01-2
Molecular Formula	C96H155N29O28S2
Molecular Weight	2187.6 g/mol
Synonyms	Tissue Factor (33-53) (Cys39) peptide; TF (33-53) Cys39; Human Tissue Factor residues 33-53 (Cys39); Coagulation Factor III (33-53) fragment; Thromboplastin (33-53) peptide; F3 (33-53) peptide; CD142 (33-53) fragment; H-Tyr-Lys-Asn-Leu-Glu-Glu-Cys-Pro-Lys-Glu-Asp-Glu-Glu-Leu-Phe-Lys-Gln-Asp-Lys-Val-Asn-NH2 (Disulfide bridge: Cys7-Cys39)
EINECS	Contact for details

Quality Control

Our (Cys39)-Tissue Factor (33-53) is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). A detailed Certificate of Analysis (COA) documenting purity, peptide content, and solvent residues is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the lyophilized powder at -20°C or below. Once reconstituted, aliquot the solution to avoid repeated freeze-thaw cycles and store at -80°C. The product is hygroscopic (moisture-sensitive); ensure the vial is equilibrated to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Molecular Weight	2187.6 ± 2.0 Da (by MS)
Solvent Residues	Meets ICH guidelines
Water Content (K.F.)	≤ 5.0%
Biological Activity	Assay-dependent; data available on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.