Description

2-Chloro-4-Fluorophenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and organic electronic components.

Application

• Pharmaceutical Intermediate: A key synthon for constructing biaryl structures found in numerous drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science: Serves as a monomer or precursor in the development of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for methodology development and library synthesis.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	2-Chloro-4-Fluorophenylboronic Acid
CAS No.	313545-72-1
Molecular Formula	C6H5BClFO2
Molecular Weight	173.37 g/mol
Synonyms	(2-Chloro-4-fluorophenyl)boronic acid; 2-Chloro-4-fluorobenzeneboronic acid; B-(2-Chloro-4-fluorophenyl)boronic acid; 2-Chloro-4-fluorophenylboronic acid pinacol ester (common derivative); 2-Cl-4-F-PhB(OH)2; CAS 313545-72-1
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Fluorophenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment to guarantee batch-to-batch consistency and reliability for your processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.