Description

2-Chloro-4-Isopropoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific chlorinated phenylboronic acid structures.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile electrophilic or nucleophilic partner in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and functional materials.
• Material Science Research: A building block for organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and sensors for biological research.

Basic Information

Item	Details
Product Name	2-Chloro-4-Isopropoxyphenylboronic Acid
CAS No.	313545-47-0
Molecular Formula	C9H12BClO3
Molecular Weight	214.45 g/mol
Synonyms	(2-Chloro-4-isopropoxyphenyl)boronic acid; 2-Chloro-4-isopropoxybenzeneboronic acid; 2-Chloro-4-(1-methylethoxy)benzeneboronic acid; Boronic acid, B-(2-chloro-4-isopropoxyphenyl)-; 313545-47-0; 2-Chloro-4-isopropoxy phenylboronic acid; 4-Isopropoxy-2-chlorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Isopropoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with high-grade chemical standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.