Description

4-Isopropoxy-2-(Trifluoromethyl)Phenylboronic Acid is a high-value organoboron compound, specifically a substituted phenylboronic acid, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This advanced intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific trifluoromethyl-substituted aromatic systems.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its boronic acid group facilitates polymerization or functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and sensors that leverage boronic acid-diol interactions for detecting sugars or other biomolecules.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales, from laboratory to pilot plant.

Basic Information

Product Name	4-Isopropoxy-2-(Trifluoromethyl)Phenylboronic Acid
CAS No.	313545-40-3
Molecular Formula	C10H12BF3O3
Molecular Weight	248.01 g/mol
Synonyms	[4-(1-Methylethoxy)-2-(trifluoromethyl)phenyl]boronic acid; 2-Trifluoromethyl-4-isopropoxyphenylboronic acid; 4-Isopropoxy-2-(trifluoromethyl)benzeneboronic acid; (4-Isopropoxy-2-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[4-(1-methylethoxy)-2-(trifluoromethyl)phenyl]-; 4-iso-Propoxy-2-trifluoromethylphenylboronic acid
EINECS	Contact for details

Quality Control

Our production of 4-Isopropoxy-2-(Trifluoromethyl)Phenylboronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ICH guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.