Description

(2-Chloro-4-(Difluoromethoxy)Phenyl)Boronic Acid(Wxfc0672) is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active ingredients and novel organic compounds. The CAS number for this substance is 313545-33-4.

Application

This specialized boronic acid ester serves as a key synthetic intermediate in several high-value industries:

• Pharmaceutical Intermediate: Critical for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in constructing biaryl and heterobiaryl scaffolds common in modern therapeutics.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific halogenated and difluoromethoxy-substituted aromatic systems.
• Ligand & Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as those for OLEDs and organic photovoltaics, where its structure can be incorporated into conjugated polymers.
• Chemical Biology & Probe Synthesis: Useful for creating molecular probes and tags for bio-conjugation and labeling applications due to its reactive boronic acid group.

Basic Information

Product Name	(2-Chloro-4-(Difluoromethoxy)Phenyl)Boronic Acid(Wxfc0672)
CAS No.	313545-33-4
Molecular Formula	C7H6BClF2O3
Molecular Weight	222.38 g/mol
Synonyms	(2-Chloro-4-(difluoromethoxy)phenyl)boronic acid; B-(2-Chloro-4-(difluoromethoxy)phenyl)boronic acid; 2-Chloro-4-(difluoromethoxy)benzeneboronic acid; [2-Chloro-4-(difluoromethoxy)phenyl]boronic acid; Wxfc0672; Boronic acid, B-[2-chloro-4-(difluoromethoxy)phenyl]-; 313545-33-4
EINECS	Contact for details

Quality Control

Our (2-Chloro-4-(Difluoromethoxy)Phenyl)Boronic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles. We adhere to cGMP standards where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.