Description

n-(5-Bromopyridin-2-Yl)-3,4,5-Trimethoxybenzamide CAS NO 312943-96-7 is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine and benzamide structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapeutics, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, particularly in oncology and neurology research.
• Kinase Inhibitor Development: Used as a core scaffold or a functionalized fragment for designing and optimizing novel kinase inhibitors due to its bromopyridine moiety.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.
• Chemical Biology Probes: Utilized in the creation of chemical probes for studying specific biological pathways and protein functions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	n-(5-Bromopyridin-2-Yl)-3,4,5-Trimethoxybenzamide
CAS No.	312943-96-7
Molecular Formula	C15H15BrN2O4
Molecular Weight	367.20 g/mol
Synonyms	3,4,5-Trimethoxy-N-(5-bromopyridin-2-yl)benzamide; 5-Bromo-2-[(3,4,5-trimethoxybenzoyl)amino]pyridine; N-(5-Bromo-2-pyridinyl)-3,4,5-trimethoxybenzamide; 312943-96-7; Benzamide, N-(5-bromo-2-pyridinyl)-3,4,5-trimethoxy-
EINECS	Contact for details

Quality Control

Our n-(5-Bromopyridin-2-Yl)-3,4,5-Trimethoxybenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.