Description

2-Methoxy-4-(Trifluoromethyl)-Phenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing trifluoromethyl-substituted biaryl motifs.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Building block for organic electronic materials, such as ligands for catalysts and monomers for specialty polymers.
• Chemical Biology & Medicinal Chemistry: Employed in fragment-based drug discovery and the development of molecular probes.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical suppliers offering bespoke synthesis services.

Basic Information

Product Name	2-Methoxy-4-(Trifluoromethyl)-Phenylboronic Acid
CAS No.	312936-89-3
Molecular Formula	C9H8BF3O3
Molecular Weight	232.0 g/mol
Synonyms	[2-Methoxy-4-(trifluoromethyl)phenyl]boronic acid; 2-Methoxy-4-(trifluoromethyl)benzeneboronic acid; (2-Methoxy-4-(trifluoromethyl)phenyl)boronic acid; 4-Trifluoromethyl-2-methoxyphenylboronic acid; 2-Methoxy-α,α,α-trifluoro-p-tolylboronic acid; Boronic acid, B-[2-methoxy-4-(trifluoromethyl)phenyl]-; CAS 312936-89-3
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-(Trifluoromethyl)-Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.