Description

Pyruvic-1,2-13C2 Acid Sodium Salt is a stable, isotopically labeled sodium salt of pyruvic acid, specifically enriched with carbon-13 at the 1 and 2 positions. This high-purity labeled compound is essential for advanced metabolic research and analytical method development, providing a critical tracer for studying biochemical pathways. It is primarily required by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in NMR spectroscopy, mass spectrometry, and metabolic flux analysis.

Application

• Metabolic Tracer Studies: Used in 13C-NMR and LC-MS based metabolic flux analysis (MFA) to map central carbon metabolism in cells, tissues, or microorganisms.
• Pharmaceutical Research: Serves as a key labeled intermediate in the synthesis of isotopically labeled active pharmaceutical ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Diagnostic Agent Development: Employed in the research and production of potential contrast agents or probes for magnetic resonance imaging (MRI) and spectroscopic applications.
• Biochemical Assay Standard: Acts as a high-purity internal standard or calibration standard in quantitative mass spectrometry for accurate measurement of pyruvate and related metabolites in complex biological samples.
• Enzymology Studies: Utilized to investigate the kinetics and mechanisms of enzymes involved in glycolysis, gluconeogenesis, and the citric acid cycle.
• Nutritional & Sports Science Research: Applied in studies examining energy metabolism, lactate dynamics, and mitochondrial function.

Basic Information

Product Name	Pyruvic-1,2-13C2 Acid Sodium Salt
CAS No.	312623-97-5
Molecular Formula	C132H3NaO3
Molecular Weight	112.03 (for 13C2 labeled form)
Synonyms	Sodium Pyruvate-1,2-13C2; 2-Oxopropanoic-1,2-13C2 Acid Sodium Salt; Pyruvic Acid-1,2-13C2 Sodium Salt; [1,2-13C2]Pyruvic Acid Sodium Salt; Sodium 2-Oxopropanoate-1,2-13C2; Na Pyruvate-1,2-13C2; 13C2-Labeled Sodium Pyruvate
EINECS	Contact for details

Quality Control

Our Pyruvic-1,2-13C2 Acid Sodium Salt is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is characterized by advanced analytical techniques including NMR and mass spectrometry to confirm isotopic enrichment and identity. Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and specific analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to 13C labeling pattern
Assay (HPLC)	≥ 98.0% (Chemical Purity)
Isotopic Enrichment	≥ 99 atom % 13C at positions 1 & 2
Water Content (KF)	≤ 2.0 %
pH (5% solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.