Description

2-[5-(Trifluoromethyl)Isoxazol-3-Yl]Phenol is a high-value fluorinated heterocyclic building block. This compound is critical for the synthesis of advanced agrochemicals and pharmaceuticals, where its unique trifluoromethyl-isoxazole-phenol scaffold imparts desirable biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for creating novel active ingredients and intermediates.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and isoxazole groups.
• Pharmaceutical Building Block: Used in medicinal chemistry for constructing drug candidates targeting various diseases, where the phenol moiety allows for further functionalization.
• Material Science Research: Serves as a precursor for specialty polymers and advanced materials requiring fluorinated aromatic components.
• Ligand Synthesis: Utilized in organometallic chemistry for creating novel ligands in catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and scale-up projects.

Basic Information

Product Name	2-[5-(Trifluoromethyl)Isoxazol-3-Yl]Phenol
CAS No.	312505-97-8
Molecular Formula	C10H6F3NO2
Molecular Weight	229.16 g/mol
Synonyms	3-Hydroxy-5-(trifluoromethyl)isoxazole; 5-(Trifluoromethyl)-3-isoxazolol; 2-(5-(Trifluoromethyl)isoxazol-3-yl)phenol; Phenol, 2-[5-(trifluoromethyl)-3-isoxazolyl]-; 3-Phenol-5-(trifluoromethyl)isoxazole
EINECS	Contact for details

Quality Control

Our 2-[5-(Trifluoromethyl)Isoxazol-3-Yl]Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.