Description

2-(2-Oxo-2-(4-(Trifluoromethyl)Phenyl)Ethyl)Malononitrile is a specialized organic building block featuring a trifluoromethylphenyl ketone moiety linked to a reactive malononitrile group. This compound matters for its role as a key intermediate in the synthesis of complex heterocyclic and fluorinated molecules, offering a versatile handle for further chemical elaboration. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active ingredients and novel chemical entities. The CAS number for this compound is 312308-30-8.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of drug candidates, particularly those requiring the incorporation of a trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the unique properties of the CF3 group improve product efficacy.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Fluorine Chemistry: A valuable scaffold for exploring new reactions and methodologies in organofluorine chemistry, a field vital for modern life sciences.
• Heterocyclic Compound Construction: The reactive nitrile and ketone functionalities make it an ideal starting material for constructing pyridine, pyrimidine, and other nitrogen-containing heterocycles.

Basic Information

Product Name	2-(2-Oxo-2-(4-(Trifluoromethyl)Phenyl)Ethyl)Malononitrile
CAS No.	312308-30-8
Molecular Formula	C12H7F3N2O
Molecular Weight	252.20 g/mol
Synonyms	2-[2-Oxo-2-[4-(trifluoromethyl)phenyl]ethyl]propanedinitrile; 2-(2-Oxo-2-(4-(Trifluoromethyl)Phenyl)Ethyl)Malononitrile; 2-(4-Trifluoromethylbenzoyl)acetonitrile dicyanomethylene derivative; α-(4-Trifluoromethylbenzoyl)malononitrile; (4-Trifluoromethylbenzoyl)acetonitrile cyanomethylene derivative; Propanedinitrile, 2-[2-oxo-2-[4-(trifluoromethyl)phenyl]ethyl]-; 312308-30-8
EINECS	Contact for details

Quality Control

Our 2-(2-Oxo-2-(4-(Trifluoromethyl)Phenyl)Ethyl)Malononitrile is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.