Description

Amyloid β-Protein (20-29) is a synthetic peptide fragment corresponding to residues 20-29 of the amyloid-beta protein, a key component in Alzheimer's disease research. This high-purity peptide is critical for studying the aggregation mechanisms, neurotoxicity, and structural properties of full-length amyloid-beta. It is an essential biochemical tool for pharmaceutical R&D, academic neuroscience, and diagnostic development focused on neurodegenerative disorders.

Application

• Biochemical Research: Fundamental studies on amyloid-beta peptide aggregation kinetics, fibril formation, and structural characterization.
• Drug Discovery & Screening: Used as a target or reference compound in high-throughput assays to identify and evaluate potential therapeutic inhibitors of amyloid aggregation.
• Antibody & Assay Development: Serves as a critical antigen for the production and validation of antibodies, ELISA kits, and other immunoassays targeting amyloid-beta epitopes.
• Neuroscience & Toxicology Studies: Investigation of peptide-induced cytotoxicity and neuroinflammatory pathways in cellular models of Alzheimer's disease.
• Reference Standard: Acts as a chromatographic and mass spectrometry standard for the analysis of amyloid-beta peptides and related metabolites.
• Material Science Applications: Study of self-assembling peptide nanomaterials and their biophysical properties.

Basic Information

Product Name	Amyloid β-Protein (20-29)
CAS No.	311818-43-6
Molecular Formula	C50H78N14O15
Molecular Weight	1083.2 g/mol
Synonyms	Aβ (20-29); Amyloid β-Protein (20-29) fragment; Amyloid β-Peptide (20-29); H-Val-Gly-Gly-Val-Val-Ile-Ala-OH; Aβ20-29; Amyloid-β (20-29); β-Amyloid Protein (20-29); Alzheimer's Disease Amyloid Peptide (20-29)
EINECS	Contact for details

Quality Control

Our Amyloid β-Protein (20-29) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research-grade biochemicals, ensuring reliability for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Solubility	Soluble in water, DMSO, or acetic acid solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.