Description

4-Pentenoicacid,2-Amino-2-(Hydroxymethyl)-,Methylester,(2S)-(9Ci) CAS NO 311345-45-6 is a high-purity, chiral amino acid derivative characterized by its pentenoic acid backbone and hydroxymethyl functionality. This compound is a critical chiral building block for the synthesis of complex pharmaceutical intermediates and bioactive molecules, offering precise stereochemical control. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder research.
• Peptidomimetics & Drug Discovery: Serves as a constrained, unsaturated amino acid analog in the design of peptide mimics and small molecule libraries for high-throughput screening.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and plant growth regulators with specific chiral activity.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Bioconjugation & Linker Chemistry: The reactive alkene and ester groups facilitate its use in creating bioconjugates and cleavable linkers for prodrug strategies.
• Material Science Research: Investigated as a monomer or cross-linker for the development of functionalized polymers with specific biological or chemical properties.

Basic Information

Product Name	4-Pentenoicacid,2-Amino-2-(Hydroxymethyl)-,Methylester,(2S)-(9Ci)
CAS No.	311345-45-6
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(2S)-2-Amino-2-(hydroxymethyl)-4-pentenoic acid methyl ester; Methyl (2S)-2-amino-2-(hydroxymethyl)-4-pentenoate; L-2-Amino-2-(hydroxymethyl)-4-pentenoic acid methyl ester; (S)-2-Amino-2-(hydroxymethyl)-4-pentenoic acid methyl ester; 4-Pentenoic acid, 2-amino-2-(hydroxymethyl)-, methyl ester, (2S)-; A chiral serine derivative; A hydroxymethyl glutamic acid analog
EINECS	Contact for details

Quality Control

Our production of 4-Pentenoicacid,2-Amino-2-(Hydroxymethyl)-,Methylester,(2S)-(9Ci) adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development grade specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.