Description

Rfamide-Related Peptide-1 (Human) CAS NO 311309-25-8 is a synthetic neuropeptide analog that plays a significant role in modulating the hypothalamic-pituitary-gonadal axis and energy homeostasis. This high-purity peptide is critical for advanced research in neuroendocrinology and metabolic regulation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutics for reproductive disorders and metabolic diseases.

Application

• Neuroscience Research: Investigation of its role as a potent agonist of the GPR147 receptor and its effects on gonadotropin secretion.
• Endocrine Disorder Studies: Fundamental research into the mechanisms of puberty, fertility, and related hormonal pathways.
• Metabolic Research: Exploration of its anorexigenic effects and potential links to obesity and energy balance.
• Drug Discovery & Development: Serving as a reference standard and a key intermediate in the development of novel neuropeptide-based therapeutics.
• In Vitro & In Vivo Assays: Use in functional cellular assays and animal model studies to elucidate physiological roles and therapeutic potential.
• Biomarker Development: Potential use in developing diagnostic tools for endocrine and metabolic conditions.

Basic Information

Product Name	Rfamide-Related Peptide-1 (Human)
CAS No.	311309-25-8
Molecular Formula	C85H134N28O23S2
Molecular Weight	1972.3 g/mol
Synonyms	RFRP-1 (Human); RFamide Related Peptide-1; hRFRP-1; Neuropeptide VF (143-153) (Human); LPPSLPQRF-NH2; GPR147 Agonist; Gonadotropin-Inhibitory Hormone (GnIH) Related Peptide; Kisspeptin Antagonist Related Peptide; AVPRF-NH2 (sequence-based); 311309-25-8
EINECS	Contact for details

Quality Control

Our Rfamide-Related Peptide-1 (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the lyophilized powder under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.