Description

Cyclopentanecarboxamide, 1-Amino-2-(1-Methylethyl)-, (1S,2R)- (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. This compound matters because its unique bicyclic, amide-functionalized structure provides a versatile scaffold for constructing complex molecules with precise three-dimensional orientation. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its defined stereochemistry at the 1S,2R positions is critical for biological activity and selectivity.

Application

• Pharmaceutical Intermediate: A key chiral building block for the research and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereospecificity.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure herbicides, fungicides, and insecticides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and catalysts used in enantioselective transformations.
• Fine Chemical and Specialty Chemical Production: Employed in the multistep synthesis of complex fragrance molecules, flavors, and other high-value specialty chemicals.
• Academic and Industrial R&D: A valuable compound for methodological studies in organic chemistry, including new route development and stereochemistry research.

Basic Information

Product Name	Cyclopentanecarboxamide, 1-Amino-2-(1-Methylethyl)-, (1S,2R)- (9Ci)
CAS No.	309757-00-4
Molecular Formula	C9H18N2O
Molecular Weight	170.25 g/mol
Synonyms	(1S,2R)-1-Amino-2-isopropylcyclopentanecarboxamide; (1S,2R)-1-Amino-2-(propan-2-yl)cyclopentane-1-carboxamide; 1-Amino-2-isopropylcyclopentanecarboxamide (1S,2R)-; 309757-00-4; (1S,2R)-AICA; cis-1-Amino-2-isopropylcyclopentanecarboxamide; Cyclopentanecarboxamide, 1-amino-2-(1-methylethyl)-, (1S,2R)-; (1S,2R)-1-Amino-2-isopropyl-cyclopentanecarboxylic acid amide
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxamide, 1-Amino-2-(1-Methylethyl)-, (1S,2R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1S,2R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.