Description

Carbamic Acid, [1-(Hydroxymethyl)-2-Methylcyclopropyl]-, 1,1-Dimethylethyl Ester is a specialized organic compound featuring a unique cyclopropane ring structure. This molecule is of significant interest as a key synthetic intermediate in advanced pharmaceutical research and fine chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a constrained cyclopropane scaffold.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the cyclopropane moiety can impart specific biological activity.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex molecules in custom synthesis and material science applications.
• Protease Inhibitor Development: The carbamate and hydroxymethyl functional groups make it relevant for designing enzyme inhibitors.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	Carbamic Acid, [1-(Hydroxymethyl)-2-Methylcyclopropyl]-, 1,1-Dimethylethyl Ester
CAS No.	308266-28-6
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	tert-Butyl (1-(hydroxymethyl)-2-methylcyclopropyl)carbamate; N-Boc-1-(hydroxymethyl)-2-methylcyclopropanamine; 1-(Hydroxymethyl)-2-methylcyclopropylcarbamic acid tert-butyl ester; (1-(Hydroxymethyl)-2-methylcyclopropyl)carbamic acid tert-butyl ester; Boc-Protected 1-(hydroxymethyl)-2-methylcyclopropylamine; N-(tert-Butoxycarbonyl)-1-(hydroxymethyl)-2-methylcyclopropanamine; 308266-28-6
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [1-(Hydroxymethyl)-2-Methylcyclopropyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.