Description

Benzene, 5-Butyl-1,3-Difluoro-2-Iodo- is a halogenated benzene derivative of significant interest in advanced organic synthesis and materials science. This compound serves as a versatile and valuable building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Its unique substitution pattern makes it an essential intermediate for researchers and manufacturers specializing in fine chemical production, ligand synthesis, and the creation of novel functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluoro and iodo substituents confer specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and polymers with tailored optical or electronic properties.
• Fluorinated Compound Library: A valuable reagent for building fluorinated compound libraries in medicinal chemistry for drug discovery programs.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.

Basic Information

Item	Details
Product Name	Benzene, 5-Butyl-1,3-Difluoro-2-Iodo-
CAS No.	308117-05-7
Molecular Formula	C10H11F2I
Molecular Weight	296.10 g/mol
Synonyms	5-Butyl-1,3-difluoro-2-iodobenzene; 2-Iodo-5-butyl-1,3-difluorobenzene; 1,3-Difluoro-5-butyl-2-iodobenzene; 2-Iodo-1,3-difluoro-5-butylbenzene; 5-Butyl-2-iodo-1,3-difluorobenzene; 1,3-Difluoro-2-iodo-5-butylbenzene; Butyl-difluoro-iodobenzene
EINECS	Contact for details

Quality Control

Our Benzene, 5-Butyl-1,3-Difluoro-2-Iodo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.