Description

2-(Trifluoromethylsulfanyl)Ethanol is a specialized organofluorine building block characterized by the presence of both a trifluoromethylthio (SCF₃) group and a hydroxyl functionality. This unique bifunctional structure makes it a valuable intermediate for introducing the highly lipophilic and metabolically stable SCF₃ moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those requiring the lipophilic trifluoromethylthio group to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the SCF₃ group can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and transition metal catalysis.
• Advanced Material Precursor: Employed in the synthesis of functional polymers and liquid crystals with unique surface properties and chemical resistance.
• Fluorine Chemistry Research: A critical reagent for academic and industrial research exploring new methodologies for C-SCF₃ bond formation and the properties of fluorinated compounds.

Basic Information

Product Name	2-(Trifluoromethylsulfanyl)Ethanol
CAS No.	307337-29-7
Molecular Formula	C₃H₅F₃OS
Molecular Weight	146.13 g/mol
Synonyms	2-(Trifluoromethylthio)ethanol; 2-(Trifluoromethylsulfanyl)ethan-1-ol; 2-Hydroxyethyl trifluoromethyl sulfide; Ethanol, 2-[(trifluoromethyl)thio]-; S-Trifluoromethyl-2-mercaptoethanol; 1-Hydroxy-2-(trifluoromethylthio)ethane; β-Hydroxyethyl trifluoromethyl sulfide; Trifluoromethyl 2-hydroxyethyl sulfide
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethylsulfanyl)Ethanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including NMR (¹H, ¹³C, ¹⁹F), GC/HPLC for purity, and Karl Fischer titration for water content to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and incompatible with strong bases and fluorides; keep away from such materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
NMR Purity (¹H, ¹³C, ¹⁹F)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.