Description

2-(2-Cyano-3-Fluoro)-2-(Thien-2-Yl)Acetonitrile 97% is a high-purity, fluorinated heterocyclic nitrile building block, essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine and cyano groups is critical for modulating biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, including potential pharmaceuticals, crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and metabolic stability.
• Material Science: Serves as a precursor for functionalized polymers, liquid crystals, or organic electronic materials due to its conjugated thiophene and nitrile groups.
• Chemical Synthesis: Acts as a versatile synthon for constructing complex heterocycles via cyclization reactions or as a handle for further functional group transformations.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and exploring new chemical spaces in fluoroorganic chemistry.

Basic Information

Product Name	2-(2-Cyano-3-Fluoro)-2-(Thien-2-Yl)Acetonitrile 97%
CAS No.	306976-61-4
Molecular Formula	C7H3FN2S
Molecular Weight	166.18 g/mol
Synonyms	2-(2-Cyano-3-fluorothiophen-2-yl)acetonitrile; 2-(3-Fluoro-2-cyanothiophen-2-yl)acetonitrile; 2-(3-Fluoro-2-cyanothien-2-yl)acetonitrile; 2-(3-Fluoro-2-thiophenecarbonitrile)acetonitrile; (3-Fluoro-2-cyanothiophen-2-yl)acetonitrile; 306976-61-4; Fluorinated thiophene nitrile derivative
EINECS	Contact for details

Quality Control

Our 2-(2-Cyano-3-Fluoro)-2-(Thien-2-Yl)Acetonitrile 97% is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the specified standard of ≥97%. Certificates of Analysis (COA) detailing all test results are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.