Description

(E)-4-Oxo-4-((2-(Trifluoromethyl)Phenyl)Amino)But-2-Enoic Acid is a high-purity, synthetic organic compound characterized by its enone and anilide structure. This chemical serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for the synthesis of novel active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new therapeutic entities.
• Agrochemical Development: Serves as a precursor in the research and development of new herbicides, fungicides, or plant growth regulators.
• Chemical Synthesis: Valuable scaffold for constructing more complex heterocyclic compounds and fine chemicals in laboratory settings.
• Academic & Institutional R&D: Employed in universities and research institutes for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	(E)-4-Oxo-4-((2-(Trifluoromethyl)Phenyl)Amino)But-2-Enoic Acid
CAS No.	306278-78-4
Molecular Formula	C11H8F3NO3
Molecular Weight	259.18 g/mol
Synonyms	(E)-4-Oxo-4-[(2-(trifluoromethyl)phenyl)amino]but-2-enoic acid; 2-Butenoic acid, 4-oxo-4-[[2-(trifluoromethyl)phenyl]amino]-, (2E)-; 4-Oxo-4-((2-(trifluoromethyl)phenyl)amino)-2-butenoic acid; (E)-4-((2-(Trifluoromethyl)phenyl)amino)-4-oxobut-2-enoic acid; N-(2-(Trifluoromethyl)phenyl)maleamic acid (E-isomer); CAS 306278-78-4; TFMPA derivative
EINECS	Contact for details

Quality Control

Our production of (E)-4-Oxo-4-((2-(Trifluoromethyl)Phenyl)Amino)But-2-Enoic Acid adheres to stringent in-house quality protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.