Description

4,5-Dichloro-2-Methylbenzonitrile is a versatile halogenated benzonitrile derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized aromatic core for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the dichloro and nitrile functionalities.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers due to its aromatic and electron-withdrawing properties.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4,5-Dichloro-2-Methylbenzonitrile
CAS No.	306277-20-3
Molecular Formula	C8H5Cl2N
Molecular Weight	186.04 g/mol
Synonyms	2-Methyl-4,5-dichlorobenzonitrile; 4,5-Dichloro-o-tolunitrile; 2,3-Dichloro-6-cyanotoluene; 4,5-Dichloro-2-methylbenzenecarbonitrile; Benzonitrile, 4,5-dichloro-2-methyl-; 306277-20-3 (CAS); 4,5-Dichloro-2-methyl-benzonitrile
EINECS	Contact for details

Quality Control

Our 4,5-Dichloro-2-Methylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.