Description

3-Bromo-5-Chlorobenzonitrile is a high-purity halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its precise molecular structure makes it an invaluable intermediate for constructing complex molecules in research and industrial applications. This compound is primarily sought after by pharmaceutical, agrochemical, and material science industries for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the bromo and chloro substituents enable specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored electronic or optical properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags for imaging and diagnostic applications.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to its halogen functionality.

Basic Information

Item	Details
Product Name	3-Bromo-5-Chlorobenzonitrile
CAS No.	304854-55-5
Molecular Formula	C7H3BrClN
Molecular Weight	216.46 g/mol
Synonyms	5-Chloro-3-bromobenzonitrile; 3-Bromo-5-chlorobenzene carbonitrile; 3-Bromo-5-chlorophenyl cyanide; Benzonitrile, 3-bromo-5-chloro-; (3-Bromo-5-chlorophenyl)carbonitrile; 3-Bromo-5-chloro-benzonitrile; 3-Bromo-5-chloro benzonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chlorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.