Description

n-(2-Methoxyphenyl)-2-(3-Oxo-3,4-dihydro-2H-benzo[b][1,4]thiazin-2-yl)acetamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and inflammatory pathways. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to ensure the integrity and efficacy of their final drug candidates, enabling the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs, particularly in neurological and anti-inflammatory areas.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex benzothiazine-based heterocycles in custom synthesis and process development.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the cGMP production of clinical trial materials and commercial APIs.
• Academic & Institutional Research: Utilized in universities and research institutes for pharmacological studies and the development of novel therapeutic agents.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or molecular probes for biochemical and diagnostic research due to its reactive functional groups.

Basic Information

Item	Details
Product Name	n-(2-Methoxyphenyl)-2-(3-Oxo-3,4-dihydro-2H-benzo[b][1,4]thiazin-2-yl)acetamide
CAS No.	303796-68-1
Molecular Formula	C17H16N2O3S
Molecular Weight	328.38 g/mol
Synonyms	2-[(3-Oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl)acetamido]anisole; N-(2-Methoxyphenyl)-2-(3-oxo-4H-1,4-benzothiazin-2-yl)acetamide; 303796-68-1; 2-(3-Oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl)-N-(2-methoxyphenyl)acetamide; Acetamide, N-(2-methoxyphenyl)-2-(3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl)-
EINECS	Contact for details

Quality Control

Our n-(2-Methoxyphenyl)-2-(3-Oxo-3,4-dihydro-2H-benzo[b][1,4]thiazin-2-yl)acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.