Description

3-(Trifluoromethyl)-n-[3-(Trifluoromethyl)Benzyl]Benzenecarboxamide is a specialized organic compound featuring two trifluoromethyl groups, a structural motif that imparts unique physicochemical properties critical for advanced material and pharmaceutical research. This compound serves as a valuable building block and intermediate in the synthesis of complex molecules, where its fluorine content can significantly alter lipophilicity, metabolic stability, and binding affinity. It is primarily utilized by pharmaceutical R&D teams and agrochemical scientists developing novel active ingredients, as well as in materials science for creating specialty polymers and coatings.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Active Ingredient Precursor: Used in the synthesis of advanced herbicides and pesticides, leveraging the bioactivity of the trifluoromethyl group.
• Liquid Crystal & OLED Material Research: Serves as a fluorinated building block for electronic and optoelectronic materials.
• Polymer Modification: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Process Chemistry: A versatile reagent for constructing complex aromatic amide structures in laboratory and pilot-scale synthesis.
• Chemical Biology Probe Development: Used to create labeled compounds or inhibitors for studying biological pathways and protein function.

Basic Information

Product Name	3-(Trifluoromethyl)-n-[3-(Trifluoromethyl)Benzyl]Benzenecarboxamide
CAS No.	303145-01-9
Molecular Formula	C16H11F6NO
Molecular Weight	347.26 g/mol
Synonyms	N-[[3-(Trifluoromethyl)phenyl]methyl]-3-(trifluoromethyl)benzamide; 3-(Trifluoromethyl)-N-[3-(trifluoromethyl)benzyl]benzamide; α,α,α-Trifluoro-N-[[α,α,α-trifluoro-m-tolyl]methyl]-m-toluamide; 3-Trifluoromethyl-N-(3-trifluoromethylbenzyl)benzamide; Benzamide, N-[[3-(trifluoromethyl)phenyl]methyl]-3-(trifluoromethyl)-; m-Trifluoromethyl-N-(m-trifluoromethylbenzyl)benzamide
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)-n-[3-(Trifluoromethyl)Benzyl]Benzenecarboxamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical specifications. Our quality commitment ensures the material is suitable for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.