Description

2-[5-(2-Fluorobenzoyl)-2-Thienyl]Acetonitrile is a high-value, specialized organic intermediate featuring a unique molecular architecture combining fluorinated benzoyl and thiophene-acetonitrile moieties. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where its specific structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting the central nervous system, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, conductive polymers, and specialty polymers with tailored electronic properties.
• Chemical Biology & Proteomics: Employed as a building block for creating chemical probes, affinity labels, or tags used in studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP for clinical trial materials.

Basic Information

Product Name	2-[5-(2-Fluorobenzoyl)-2-Thienyl]Acetonitrile
CAS No.	303144-50-5
Molecular Formula	C13H8FNO2S
Molecular Weight	261.27 g/mol
Synonyms	2-(5-(2-Fluorobenzoyl)thiophen-2-yl)acetonitrile; 2-(5-(2-Fluorobenzoyl)-2-thienyl)ethanenitrile; 2-Fluoro-5-(2-cyanomethylthiophen-2-yl)benzophenone; 2-(5-(o-Fluorobenzoyl)thiophen-2-yl)acetonitrile; (5-(2-Fluorobenzoyl)thiophen-2-yl)acetonitrile; CAS 303144-50-5
EINECS	Contact for details

Quality Control

Every batch of 2-[5-(2-Fluorobenzoyl)-2-Thienyl]Acetonitrile is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our standard quality commitment aligns with the expectations for fine chemical intermediates used in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.