Description

4-Bromo-n-tert-Butyl-3-Fluorobenzamide is a high-purity, halogenated benzamide derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates bromine and fluorine substituents on an aromatic ring, enabling precise structural modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other small molecule therapeutics.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, or pesticides where the tert-butyl and halogen groups contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its rigid, substituted benzene core.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-Bromo-n-tert-Butyl-3-Fluorobenzamide
CAS No.	303084-63-1
Molecular Formula	C11H13BrFNO
Molecular Weight	274.13 g/mol
Synonyms	4-Bromo-N-(tert-butyl)-3-fluorobenzamide; 3-Fluoro-4-bromo-N-tert-butylbenzamide; N-tert-Butyl-4-bromo-3-fluorobenzamide; Benzamide, 4-bromo-N-(1,1-dimethylethyl)-3-fluoro-; 4-Bromo-3-fluoro-N-(tert-butyl)benzamide; 4-Bromo-N-(tert-butyl)-3-fluorobenzoic acid amide
EINECS	Contact for details

Quality Control

Our 4-Bromo-n-tert-Butyl-3-Fluorobenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.