Description

n-Benzyl-5-Bromo-Nicotinamide is a high-purity brominated nicotinamide derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting neurological disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the preparation of novel herbicides, fungicides, and plant growth regulators requiring brominated pyridine motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and photoactive compounds due to its bromine handle for further functionalization.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	n-Benzyl-5-Bromo-Nicotinamide
CAS No.	303031-43-8
Molecular Formula	C13H11BrN2O
Molecular Weight	291.15 g/mol
Synonyms	5-Bromo-N-benzylnicotinamide; 5-Bromo-N-(phenylmethyl)-3-pyridinecarboxamide; 3-Pyridinecarboxamide, 5-bromo-N-(phenylmethyl)-; N-Benzyl-5-bromonicotinamide; 5-Bromonicotinic acid benzylamide; Benzyl 5-bromonicotinamide; 303031-43-8 (CAS); 5-Bromo-N-benzyl-3-pyridinecarboxamide
EINECS	Contact for details

Quality Control

Our n-Benzyl-5-Bromo-Nicotinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.