Description

4,5,6-Trimethyl-2-{[2-(4-Methylphenyl)-2-Oxoethyl]Sulfanyl}Pyridine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. Pharmaceutical R&D departments and fine chemical manufacturers need this material to develop next-generation drug candidates, leveraging its unique pyridine-carbonitrile core for targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where its heterocyclic structure contributes to specific modes of action.
• Material Science: Serves as a monomer or ligand in the creation of specialized polymers and metal-organic frameworks (MOFs) with tailored properties.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex molecules due to its reactive nitrile and sulfanyl groups.
• Ligand for Catalysis: Potential application in designing novel catalysts for asymmetric synthesis and cross-coupling reactions.

Basic Information

Item	Detail
Product Name	4,5,6-Trimethyl-2-{[2-(4-Methylphenyl)-2-Oxoethyl]Sulfanyl}Pyridine-3-Carbonitrile
CAS No.	303017-52-9
Molecular Formula	C18H18N2OS
Molecular Weight	310.41 g/mol
Synonyms	2-[(2-(4-Methylphenyl)-2-oxoethyl)thio]-4,5,6-trimethyl-3-pyridinecarbonitrile; 4,5,6-Trimethyl-2-[(2-(p-tolyl)-2-oxoethyl)thio]nicotinonitrile; 3-Cyano-4,5,6-trimethyl-2-{[2-(4-methylphenyl)-2-oxoethyl]thio}pyridine; CAS 303017-52-9; p-Methylphenacylthio derivative of trimethylpyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 4,5,6-Trimethyl-2-{[2-(4-Methylphenyl)-2-Oxoethyl]Sulfanyl}Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.