Description

D-Proline, 3,4-Dihydroxy-, (3R,4R)- (9Ci) is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry at the 3 and 4 positions. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug candidates, including enzyme inhibitors and receptor modulators.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for stereoselective reactions.
• Biochemical Research: Serves as a standard or reagent in studies of proline metabolism, enzyme mechanisms, and peptide mimetics.
• Agrochemical Synthesis: Intermediate in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Peptidomimetics & Drug Design: Incorporated into peptide analogs to modify biological activity, stability, and pharmacokinetic properties.
• Fine Chemical Production: Building block for the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	D-Proline, 3,4-Dihydroxy-, (3R,4R)- (9Ci)
CAS No.	302593-22-2
Molecular Formula	C₅H₉NO₃
Molecular Weight	131.13 g/mol
Synonyms	(3R,4R)-3,4-Dihydroxy-D-proline; (3R,4R)-3,4-Dihydroxypyrrolidine-2-carboxylic acid; D-3,4-Dihydroxyproline; (2R,3R,4R)-3,4-Dihydroxypyrrolidine-2-carboxylic acid; 302593-22-2; (3R,4R)-DHDP; D-cis-3,4-Dihydroxyproline
EINECS	Contact for details

Quality Control

Our D-Proline, 3,4-Dihydroxy-, (3R,4R)- (9Ci) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.